Recent Developments in Ventricular Assist Device Therapy
5. Recent Developments in Ventricular Assist Device Therapy
Recent Developments in Ventricular Assist Device Therapy
作者: Angel Moctezuma-Ramirez et al. 年份: 2025 期刊: Rev Cardiovasc Med DOI: 10.31083/RCM25440
证据等级: 待评估 IF: 待补充
中文核心摘要（150 字以内）：
左心室辅助装置(LVADs)从大型脉冲式系统向紧凑型连续流泵的演变显著改善了植入结局和患者活动性。微创手术技术的出现为LVAD受体提供了降低发病率和增强恢复的益处。无线电力传输技术的创新旨在减轻驱动线相关并发症，提高患者安全性和生活质量。儿童心室辅助装置(VADs)仍是关键的未满足需求；开发儿童VADs的挑战包括装置尺寸和先天性心脏病的治疗。LVAD技术适应用于右心室辅助装置(RVADs)的进展使得在急性心脏状况或先天性心脏缺陷患者中有效治疗右心衰竭成为可能。为了解决机械循环支持(MCS)获取的差异，国际上开发了成本效益型VAD设计。来自墨西哥城的Vitalmex装置将脉冲流技术与体外设计相结合，利用硅弹性材料和钛等成本效益材料，并具有可重复使用的泵壳以最小化制造和运营成本。罗马尼亚研究人员使用先进的数学建模和三维(3D)打印生产了轮缘驱动、无轮毂轴流泵，实现高效血流，具有紧凑设计，包括无线电源以降低感染风险。总之，MCS继续通过技术创新和全球合作取得进展。持续努力对于优化结局、扩大适应症和改善全球生命挽救疗法的获取至关重要。
关键词：Ventricular Assist Device, LVAD, RVAD, 机械循环支持, 无线电力传输, 儿童VAD
🔗 PubMed 🔗 Semantic Scholar 📄 PDF 📥 BibTeX
📖 英文原文摘要
The evolution of left ventricular assist devices (LVADs) from large, pulsatile systems to compact, continuous-flow pumps has significantly improved implantation outcomes and patient mobility. Minimally invasive surgical techniques have emerged that offer reduced morbidity and enhanced recovery for LVAD recipients. Innovations in wireless power transfer technologies aim to mitigate driveline-related complications, enhancing patient safety and quality of life. Pediatric ventricular assist devices (VADs) remain a critical unmet need; challenges in developing pediatric VADs include device sizing and managing congenital heart disease. Advances in LVAD technology adapted for use in right ventricular assist devices (RVADs) make possible the effective management of right ventricular failure in patients with acute cardiac conditions or congenital heart defects. To address disparities in mechanical circulatory support (MCS) access, cost-effective VAD designs have been developed internationally. The Vitalmex device from Mexico City combines pulsatile-flow technology with a paracorporeal design, utilizing cost-effective materials like silicone-elastic and titanium, and features a reusable pump housing to minimize manufacturing and operational costs. Romanian researchers have used advanced mathematical modeling and three-dimensional (3D) printing to produce a rim-driven, hubless axial-flow pump, achieving efficient blood flow with a compact design that includes a wireless power supply to reduce infection risk. In conclusion, MCS continues to advance with technological innovation and global collaboration. Ongoing efforts are essential to optimize outcomes, expand indications, and improve access to life-saving therapies worldwide.
Keywords: LVAD; RVAD support; cost-effective VAD; minimally invasive surgery; pediatric VAD; wireless LVAD.
最后更新：2026-02-27 🔝 返回顶部